Synthesis and Antimicrobial Activity of Novel 2,4-Disubstituted Thiazoles
نویسندگان
چکیده
منابع مشابه
antioxidant and antimicrobial activity of allium jesdianum extract
چکیده بررسی فعالیت ضد اکسیدانی و ضدمیکروبی عصاره گیاه بن سرخ (allium jesdianum) به کوشش: زهرا مقیمی هدف از این تحقیق بررسی میزان ترکیبات فنولی کل، ترکیبات فلاوونوئیدی کل، فعالیت ضداکسیدانی و ضدمیکروبی عصاره ی گیاه تازه و خشک بن سرخ بود. استخراج عصاره به روش های غوطه وری، استفاده از همزن مغناطیسی، دستگاه مایکروویو، امواج فراصوت و گرمادهی مقاومتی و با استفاده از متانول، اتانول و آب به عنوا...
Synthesis and antimicrobial evaluation of certain novel thiazoles.
PURPOSE This article makes an attempt to synthesize certain compounds containing thiazole and imidazole moieties and screen for the antimicrobial properties. METHODS The novel compounds synthesized were characterized by elemental analysis, IR and (1)HNMR spectral data. The antimicrobial activity of novel compounds was evaluated by cup plate method. RESULTS The compound p-t showed more antib...
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A series of imidazo[2,1-b]thiazole were synthesized by reacting 4, 5-diphenylimidazole-2-thione with ketones in presence of iodine or bromine in a single step. The products were generated in good yields and characterized by standard analytical techniques such as IR, 1 H NMR, 13 C NMR and mass spectrometry. The synthesized products were also screened for their antimicrobial activities.
متن کاملSynthesis, molecular docking and QSAR studies of 2, 4-disubstituted thiazoles as antimicrobial agents
Article history: Received on: 13/11/2014 Revised on: 04/12/2014 Accepted on: 22/01/2015 Available online: 27/02/2015 In present study a series of 2,4-disubstituted thiazole derivatives was synthesized and evaluated for their in vitro antibacterial and antifungal activities against B. subtilis, E. coli, S. aureus, C. albicans and A. niger by tube dilution method. The analysis of antimicrobial ac...
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The search for better antimicrobial agent due to rapid appearance of multidrug resistant microorganism and antimicrobial properties of semicarbazones and 2,5-disubstituted 1,3,4-oxadiazoles prompted us to undertake the synthesis of a few novel N-[5-(4-substitutedphenyl)-1,3,4-oxadiazol-2-yl]-N-(4substitutedbenzaldehyde)-semicarbazone and N-[5-(4-substitutedphenyl)-1,3,4-oxadiazol-2-yl]-N-[1-(4s...
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ژورنال
عنوان ژورنال: Asian Journal of Chemistry
سال: 2013
ISSN: 0970-7077,0975-427X
DOI: 10.14233/ajchem.2013.15211